Acebutolol or abutolol is a drug to lower blood pressure in hypertension. In addition, this drug can also be used in the treatment of heart rhythm disorders or angina pectoris.

Acebutolol is a beta blocker drug that works by blocking beta receptors in the heart and blood vessels. That way, the heart rate will slow down, the tension in the heart and blood vessels will decrease, and blood pressure will drop.

What is Acebutolol

The groupPrescription drugs
CategoryBeta blockers ( beta blockers )
BenefitTreating hypertension, arrhythmia, or angina pectoris
Consumed byMature
Acebutolol for pregnant and lactating womenCategory B:  Animal studies have not demonstrated a risk to the fetus, but there are no controlled studies in pregnant women.

Acebutolol can be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Drug formCapsule

Warning Before Taking Acebutolol

Acebutolol should only be used as prescribed by a doctor. Here are some things you need to pay attention to before taking acebutolol:

  • Tell your doctor about any allergies you have. Acebutolol should not be used in patients who are allergic to this drug.
  • Tell your doctor if you have severe heart failure, heart rhythm disturbances, such as AV block or   severe bradycardia . Acetabutolol should not be used by patients with these conditions.
  • Tell your doctor if you have or have had heart disease,  Raynaud's syndrome , asthma, chronic obstructive pulmonary disease (COPD), sleep apnea , diabetes, hyperthyroidism , liver disease, myasthenia gravis , kidney disease, or depression .
  • Do not drive a vehicle or perform activities that require alertness, while taking acebutolol, as this medicine can cause dizziness .
  • Tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
  • Tell your doctor if you are taking any other medicines, including herbal medicines and supplements.
  • Tell your doctor that you are being treated with acebutolol before having any surgery or medical procedures, including dental surgery.
  • See your doctor right away if you have an allergic reaction, serious side effects, or overdose after taking acebutolol.

Acebutolol Dosage and Rules

The dose of acebutolol is determined based on the patient's condition and the body's response to the drug. The following are the doses of acebutolol for adults based on their intended use:

  • Goal: Treat hypertension
    Initial dose is 200–400 mg, 1–2 times a day. The dose may be increased after 2 weeks of treatment to 400 mg, 2 times daily. The maximum dose is 1,200 mg per day divided into several doses.
  • Goal:  Overcoming arrhythmia
    Initial dose 200 mg, 2 times a day. The dose can be increased according to the patient's response. The maximum dose is 1,200 mg per day divided into several doses.
  • Goal: Treat angina pectoris
    Initial dose is 200–400 mg, 1–2 times a day. The maximum dose is 1,200 mg per day divided into several doses.

How to Take Acebutolol Correctly

Use acebutolol as recommended by the doctor and don't forget to read the information on the drug packaging. Do not increase or decrease the dose, and do not use the drug for more than the recommended time.

Acebutolol can be taken before or after meals. Use water to swallow the capsules. Do not chew, split, or crush the capsules as this may increase the risk of side effects.

Take acebutolol at the same time every day. If you forget to take acebutolol, take this drug immediately if the break with the next consumption schedule is not too close. If it is close, ignore it and do not double the dose.

In addition to taking acebutolol, you are advised to adopt a healthy lifestyle and exercise regularly so that treatment is maximized. Pay attention to the daily diet and avoid foods that contain a lot of salt (sodium).

Check with your doctor regularly while using acebutolol so that the development of the condition can be controlled.

Store acebutolol at room temperature and place in a closed container. Avoid direct sunlight and keep out of the reach of children.

Acebutolol Interactions with Other Drugs

The use of acebutolol together with other drugs can cause several interactions, including:

  • Decreased effectiveness of acebutolol when used with nonsteroidal anti-inflammatory drugs ( NSAIDs ), such as ibuprofen
  • Increased levels of aminophylline or  theophylline  in the blood which can increase the risk of side effects, such as tremors or insomnia
  • Decreased effectiveness of nasal decongestant medications, such as ephedrine
  • Increased risk of side effects when used with diltiazem or verapamil
  • Increased effectiveness of acebutolol when used with other antihypertensive drugs, such as atenolol,  reserpine , clonidine, metoprolol or betaxolol

Side Effects and Dangers of Acebutolol

There are several side effects that can arise from the use of acebutolol, including:

  • Headache or dizziness
  • Nausea, stomach pain , diarrhea, or constipation
  • Unusual tired
  • Muscle ache
  • Insomnia

Check with a doctor if the complaints mentioned above do not go away or get worse. See your doctor right away if you have an allergic reaction to a medication or experience more serious side effects, such as:

  • Hard to breathe
  • Swelling in the legs
  • Chest pain
  • Heart rate feels very slow
  • Restless, confused, or depressed
  • Dizziness so heavy that you want to faint
  • Liver disorders, which can be characterized by dark urine, nausea and vomiting, jaundice

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